Synthesis and Characterization of Tunable Poly(Ethylene Glycol): Gelatin Methacrylate Composite Hydrogels
نویسندگان
چکیده
منابع مشابه
Synthesis and characterization of tunable poly(ethylene glycol): gelatin methacrylate composite hydrogels.
Poly(ethylene glycol) (PEG) hydrogels are popular for cell culture and tissue-engineering applications because they are nontoxic and exhibit favorable hydration and nutrient transport properties. However, cells cannot adhere to, remodel, proliferate within, or degrade PEG hydrogels. Methacrylated gelatin (GelMA), derived from denatured collagen, yields an enzymatically degradable, photocrosslin...
متن کاملSynthesis and Characterization of Nanofunctionalized Gelatin Methacrylate Hydrogels
Given the importance of the extracellular medium during tissue formation, it was wise to develop an artificial structure that mimics the extracellular matrix while having improved physico-chemical properties. That is why the choice was focused on gelatin methacryloyl (GelMA), an inexpensive biocompatible hydrogel. Physicochemical and mechanical properties were improved by the incorporation of n...
متن کاملInjectable and tunable poly(ethylene glycol) analogue hydrogels based on poly(oligoethylene glycol methacrylate).
Injectable PEG-analogue hydrogels based on poly(oligoethylene glycol methacrylate) have been developed based on complementary hydrazide and aldehyde reactive linear polymer precursors. These hydrogels display the desired biological properties of PEG, form covalent networks in situ following injection, and are easily modulated for improved control over their functionality and physiochemical prop...
متن کاملSynthesis and Characterization of Polyethylene Glycol Dinitrates
Polyethylene glycol dinitrates (PEGN) with molecular weights between 400 and 20 000 g·mol-1 were prepared from polyethylene glycols by esterification with nitric acid/sulfuric acid in dichloromethane. The products were characterized by gel permeation chromatography. The yield of PEGN increases with increasing reaction temperature (0-40 °C) however large liberation of nitrogen oxides was observe...
متن کاملCell-laden microengineered gelatin methacrylate hydrogels.
The cellular microenvironment plays an integral role in improving the function of microengineered tissues. Control of the microarchitecture in engineered tissues can be achieved through photopatterning of cell-laden hydrogels. However, despite high pattern fidelity of photopolymerizable hydrogels, many such materials are not cell-responsive and have limited biodegradability. Here, we demonstrat...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Tissue Engineering Part A
سال: 2011
ISSN: 1937-3341,1937-335X
DOI: 10.1089/ten.tea.2010.0666